Natsume has officially announced two games at E3 that I am really excited about.

Rune Factory: Tides of Destiny for PlayStation 3 & Nintendo Wii

and

Harvest Moon: The Tale of Two Towns for Nintendo 3DS and DS.

Natsume has also already announced the bonus plush for Two Towns:

An Alpaca!! Super cute. Natsume knows its stuff.

Im personally thrilled. 3DS and PS3 are the only systems I regularly play that don’t have a Rune Factory or Harvest Moon game to date. Will definately post updates as more information is released!

(Source: wii.ign.com)